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Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury
- Authors
- Llorens-Bobadilla, EnricZhao, ShengMartin-Villalba, Ana
- Description
Summary from the GEO: "Heterogeneous pools of adult neural stem cells (NSCs) contribute to brain maintenance and regeneration after injury. The balance of NSC activation and quiescence, as well as the induction of lineage-specific transcription factors, may contribute to diversity of neuronal and glial fates. To identify molecular hallmarks governing these characteristics, we performed single-cell...
- Subject
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Cell DifferentiationLateral VentriclesNeural Stem CellsTranscription, Genetic
- Access Rights
- Free to All
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High-resolution transcriptome analysis of mouse subventricular zone reveals features of stem cell lineage, anatomy, and aging
- Authors
- Laks, Dan R.Poran, AsafLaughney, Ashley MarieXie, Xuanhua P.
- Description
Summary from the GEO: "High-resolution transcriptome analysis of mouse subventricular zone reveals features of stem cell lineage, anatomy, and aging" Overall design from the GEO: "Whole SVZ dissected, FACS sorted for GFPhi, Low, negative, and Unsorted Viable (6600 cells) or Aged SVZ samples, 2 weeks, 2 months, 6 months, 12 months, FACS sorted for viable cells, undergone Drop-seq single cell RNA sequencing."
- Subject
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Lateral VentriclesNeural Stem CellsTranscriptomeTransgenes
- Access Rights
- Free to All