Deep chemoproteomic analysis of LPS-stimulated RAW264.7 cell proteome

Authors

Kentsis, Alex

Description

Unanticipated regulatory protein modifications can be discovered from the unbiased comprehensive analysis of biological systems using SAMPEI. To explore this idea, we sought to map protein modifications induced during mammalian cell differentiation, modeled by the response of mouse RAW264.7 macrophage cells to lipopolysaccharide (LPS), a potent inducer of macrophage activation and differentiation...

Subject

Cell Differentiation

Lipopolysaccharides

Liquid Chromatography-Mass Spectrometry

Macrophage Activation

Proteome

Access Rights

Free to All