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Epigenetic dysregulation from chromosomal transit in micronuclei [Chr4 ATAC-seq]
- Authors
- Agustinus, Albert S.Dameracharla, BhargaviAl-Rawi, Duaa
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
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Chromatin Immunoprecipitation SequencingChromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm Metastasis
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [RPE-1 CUT&RUN]
- Authors
- Agustinus, Albert S.Raviram, RamyaCypher, E
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
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Chromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm MetastasisSequence Analysis, DNA
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [MN CUT&RUN]
- Authors
- Agustinus, Albert S.Raviram, Ramya
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
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Chromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm MetastasisSequence Analysis, DNA
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [MMCT ATAC-seq]
- Authors
- Agustinus, Albert S.Dameracharla, BhargaviKeuper, KristinaStorchova, Zuzana
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
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Chromatin Immunoprecipitation SequencingChromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm Metastasis
- Access Rights
- Free to All
-
Epigenetic dysregulation from chromosomal transit in micronuclei [ATAC-Seq]
- Authors
- Agustinus, Albert S.Raviram, Ramya
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
-
Chromatin Immunoprecipitation SequencingChromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm Metastasis
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [DLD-1 CUT&RUN]
- Authors
- Agustinus, Albert S.Dameracharla, BhargaviLy, PeterCypher, E
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
-
Chromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm MetastasisSequence Analysis, DNA
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [DLD-1 ATAC-seq]
- Authors
- Dameracharla, BhargaviLy, Peter
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
-
Chromatin Immunoprecipitation SequencingChromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm Metastasis
- Access Rights
- Free to All
-
Epigenetic dysregulation from chromosomal transit in micronuclei [RPE-1 ATAC-Seq]
- Authors
- Raviram, Ramya
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
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Chromatin Assembly and DisassemblyChromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm Metastasis
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [RPE-1 RNA-Seq]
- Authors
- Bakhoum, Mathieu F.
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
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Chromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm MetastasisRNA-Seq
- Access Rights
- Free to All
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Epigenetic dysregulation from chromosomal transit in micronuclei [4T1 MN ATAC-Seq]
- Description
Summary from GEO: "Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications,...
- Subject
-
Chromatin Immunoprecipitation SequencingChromosomal InstabilityEpigenesis, GeneticHistonesMitosisNeoplasm Metastasis
- Access Rights
- Free to All