Summary from the GEO: "Heterogeneous pools of adult neural stem cells (NSCs) contribute to brain maintenance and regeneration after injury. The balance of NSC activation and quiescence, as well as the induction of lineage-specific transcription factors, may contribute to diversity of neuronal and glial fates. To identify molecular hallmarks governing these characteristics, we performed single-cell...

Summary from the GEO: "High-resolution transcriptome analysis of mouse subventricular zone reveals features of stem cell lineage, anatomy, and aging" Overall design from the GEO: "Whole SVZ dissected, FACS sorted for GFPhi, Low, negative, and Unsorted Viable (6600 cells) or Aged SVZ samples, 2 weeks, 2 months, 6 months, 12 months, FACS sorted for viable cells, undergone Drop-seq single cell RNA sequencing."

Summary from GEO: "A challenge for understanding the development of brain circuits is to identify the factors that instruct neurons to accomplish each developmental step at the appropriate stage. Neuronal maturation follows an intrinsic species-specific developmental pace that is extremely protracted in humans and that is retained during human pluripotent stem cells (hPSCs) differentiations. Using...