Spatiotemporal coordination at the maternal-fetal interface promotes trophoblast invasion and vascular remodeling in the first half of human pregnancy

Authors

Angelo, Michael

Greenbaum, Shirley

Van Valen, David

Jaswa, Eleni G.

9 more author(s)...

Description

Description from HuBMAP: "Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels left with a thin, discontinuous smooth muscle layer and partially lined with EVTs. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote...

Subject

Arteries

Extravillous Trophoblasts

Mass spectrometry

Maternal-Fetal Exchange

Placenta

Volume Electron Microscopy

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