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Direct Recruitment of Polycomb Repressive Complex 1 (PRC1) to Chromatin by Core Binding Transcription Factors (ChIP-Seq)
- Authors
- Yu, MingMazor, TaliHuang, HuiHuang, Hsuan-Ting14 more author(s)...
- Description
Summary from GEO: "Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian cells remain incompletely understood. In this study, we show that Bmi1, a core component of Polycomb Repressive Complex 1 (PRC1), binds directly to the Runx1/CBFbeta transcription factor complex. Genome-wide studies in megakaryocytic...
- Subject
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Binding sitesChromatin Immunoprecipitation SequencingPolycomb-Group ProteinsTranscription Factors
- Access Rights
- Free to All
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Direct Recruitment of Polycomb Repressive Complex 1 (PRC1) to Chromatin by Core Binding Transcription Factors (microarray)
- Authors
- Yu, MingMazor, TaliHuang, HuiHuang, Hsuan-Ting14 more author(s)...
- Description
Summary from GEO: "Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian cells remain incompletely understood. In this study, we show that Bmi1, a core component of Polycomb Repressive Complex 1 (PRC1), binds directly to the Runx1/CBFbeta transcription factor complex. Genome-wide studies in megakaryocytic...
- Subject
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Binding sitesPolycomb-Group ProteinsRNA, Small InterferingTranscription Factors
- Access Rights
- Free to All