Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis (mass spectrometry proteomics data)

Authors

Garg, Angad

Shuman, Stewart H.

Description

Inorganic phosphate is an essential nutrient acquired by cells from their environment. Here we characterize the adaptative responses of fission yeast to chronic phosphate starvation, during which cells enter a state of quiescence, initially fully reversible upon replenishing phosphate after 2 days but resulting in gradual loss of viability during 4 weeks of starvation. Time-resolved analyses of changes...

Subject

Liquid Chromatography-Mass Spectrometry

Maf Transcription Factors

Phosphates/metabolism

Protease Inhibitors

Proteome

RNA, Transfer

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