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  • Supplemental research data accompanying "The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans"

    Authors
    Bacusmo, Jo Marie
    Orsini, Silvia S.
    Hu, Jennifer
    DeMott, Michael
    12 more author(s)...
    Description

    Includes: a chart of t6A modification and mass spectrometry analysis in wild type ΔtsaE S. mutans UA159 and an annotated mass spectrum of a precursor ion; graphs of colony forming unit and optical density growth curves and pH profile for S. mutans UA159; graphs of normalized peak area and fold-change (biofilm vs. BHI) for t6A across growth phases; gene neighborhoods and predicted operons of S. mutans...

    Subject
    Adenosine
    Anticodon/chemistry
    Anticodon/metabolism
    Bacterial Proteins
    Bacterial Toxins
    Endoribonucleases
    Nucleic Acid Conformation
    Protein Biosynthesis
    RNA Processing, Post-Transcriptional
    RNA, Transfer, Lys
    Streptococcus mutans
    Access Rights
    Free to All
  • ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing

    Authors
    Lee, Seungjae
    Wei, Lu
    Zhang, Binglong
    Goering, Raeann
    4 more author(s)...
    Description

    Summary from GEO: "ELAV/Hu factors are conserved RNA binding proteins that play diverse roles in mRNA processing and regulation. The founding member, Drosophila Elav, was recognized as a vital neural factor 35 years ago. Nevertheless, still little is known about its impacts on the transcriptome, and potential functional overlap with its paralogs. Building on our recent findings that neural-specific...

    Subject
    3' Untranslated Regions
    Ectopic Gene Expression
    RNA Processing, Post-Transcriptional
    RNA-Binding Proteins
    Access Rights
    Free to All