Data from: Differential requirements for the RAD51 paralogs in genome repair and maintenance in human cells

Authors

Garcin, Edwige B.

Gon, Stéphanie

Sullivan, Meghan R.

Brunette, Gregory J.

9 more author(s)...

Description

From Dryad summary: "Abstract: Deficiency in several of the classical human RAD51 paralogs [RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3] is associated with cancer predisposition and Fanconi anemia. To investigate their functions, isogenic disruption mutants for each were generated in non-transformed MCF10A mammary epithelial cells and in transformed U2OS and HEK293 cells. In U2OS and HEK293 cells, viable...

Subject

DNA-Binding Proteins

Homologous Recombination

Rad51 Recombinase/deficiency

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