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Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis by a NGFR-dependent mechanism
- Authors
- Ximénez-Embún, PilarMuñoz Peralta, Javier
- Description
Description from PRIDE: "Secreted extracellular vesicles are known to influence the tumor microenvironment and promote metastasis. In this work, we have analyzed the involvement of extracellular vesicles in establishing the lymph node pre-metastatic niche by melanoma cells. We found that small extracellular vesicles (sEVs) derived from highly metastatic melanoma cell lines spread broadly through...
- Subject
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Extracellular VesiclesLymph NodesMelanomaNeoplasm MetastasisProteomicsReceptor, Nerve Growth Factor
- Access Rights
- Free to All
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Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through a NGFR-dependent mechanism
- Authors
- Molina, HenrikPeinado, Héctor
- Description
Description from PRIDE: "Secreted extracellular vesicles are known to influence the tumor microenvironment and promote metastasis. In this work, we have analyzed the involvement of extracellular vesicles in the establishment of lymph node pre-metastatic niches by melanoma cells. We found that small extracellular vesicles (sEVs) derived from highly metastatic melanoma cell lines spread broadly through...
- Subject
-
Extracellular VesiclesLymph NodesMelanomaNeoplasm MetastasisProteomicsReceptor, Nerve Growth Factor
- Access Rights
- Free to All