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  • Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis by a NGFR-dependent mechanism

    Authors
    Ximénez-Embún, Pilar
    Muñoz Peralta, Javier
    Description

    Description from PRIDE: "Secreted extracellular vesicles are known to influence the tumor microenvironment and promote metastasis. In this work, we have analyzed the involvement of extracellular vesicles in establishing the lymph node pre-metastatic niche by melanoma cells. We found that small extracellular vesicles (sEVs) derived from highly metastatic melanoma cell lines spread broadly through...

    Subject
    Extracellular Vesicles
    Lymph Nodes
    Melanoma
    Neoplasm Metastasis
    Proteomics
    Receptor, Nerve Growth Factor
    Access Rights
    Free to All
  • Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through a NGFR-dependent mechanism

    Authors
    Molina, Henrik
    Peinado, Héctor
    Description

    Description from PRIDE: "Secreted extracellular vesicles are known to influence the tumor microenvironment and promote metastasis. In this work, we have analyzed the involvement of extracellular vesicles in the establishment of lymph node pre-metastatic niches by melanoma cells. We found that small extracellular vesicles (sEVs) derived from highly metastatic melanoma cell lines spread broadly through...

    Subject
    Extracellular Vesicles
    Lymph Nodes
    Melanoma
    Neoplasm Metastasis
    Proteomics
    Receptor, Nerve Growth Factor
    Access Rights
    Free to All