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Tumors with TRK fusions (MSK, 2019): Tumors with TRK fusions based on MSK-IMPACT targeted sequencing.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of tropomyosin receptor kinase (TRK) fusion tumors. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), information about mutated genes, patient demographics, and modality. The data set also...
- Subject
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DNA Mutational AnalysisOncogene Proteins, FusionReceptor Protein-Tyrosine KinasesReceptor, trkAReceptor, trkBReceptor, trkC
- Access Rights
- Free to All
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Stat3-Bdnf-TrkB axis promotes alveolar regeneration [scRNA-seq]
- Authors
- Worthen, G ScottParis, Andrew
- Description
Summary from the GEO: "Regenerating new alveolar epithelium is essential for recovery from many lung diseases. This multi-cellular regenerative process occurs when type II alveolar pneumocytes (AT2), with support from mesenchymal niche cells, proliferate to generate more AT2 cells and transdifferentiate in type I pneumocytes. To elucidate how coordinated events between AT2 cells and mesenchyme restore...
- Subject
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Alveolar Epithelial CellsReceptor, trkBSTAT3 Transcription Factor
- Access Rights
- Free to All
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Stat3-Bdnf-TrkB axis promotes alveolar regeneration [ATAC-seq]
- Authors
- Worthen, G ScottParis, Andrew
- Description
Summary from the GEO: "Regenerating new alveolar epithelium is essential for recovery from many lung diseases. This multi-cellular regenerative process occurs when type II alveolar pneumocytes (AT2), with support from mesenchymal niche cells, proliferate to generate more AT2 cells and transdifferentiate in type I pneumocytes. To elucidate how coordinated events between AT2 cells and mesenchyme restore...
- Subject
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Alveolar Epithelial CellsReceptor, trkBSTAT3 Transcription Factor
- Access Rights
- Free to All