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Stat3-Bdnf-TrkB axis promotes alveolar regeneration [scRNA-seq]
- Authors
- Worthen, G ScottParis, Andrew
- Description
Summary from the GEO: "Regenerating new alveolar epithelium is essential for recovery from many lung diseases. This multi-cellular regenerative process occurs when type II alveolar pneumocytes (AT2), with support from mesenchymal niche cells, proliferate to generate more AT2 cells and transdifferentiate in type I pneumocytes. To elucidate how coordinated events between AT2 cells and mesenchyme restore...
- Subject
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Alveolar Epithelial CellsReceptor, trkBSTAT3 Transcription Factor
- Access Rights
- Free to All
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Stat3-Bdnf-TrkB axis promotes alveolar regeneration [ATAC-seq]
- Authors
- Worthen, G ScottParis, Andrew
- Description
Summary from the GEO: "Regenerating new alveolar epithelium is essential for recovery from many lung diseases. This multi-cellular regenerative process occurs when type II alveolar pneumocytes (AT2), with support from mesenchymal niche cells, proliferate to generate more AT2 cells and transdifferentiate in type I pneumocytes. To elucidate how coordinated events between AT2 cells and mesenchyme restore...
- Subject
-
Alveolar Epithelial CellsReceptor, trkBSTAT3 Transcription Factor
- Access Rights
- Free to All