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Adenoid Cystic Carcinoma of the Breast (MSK, J Pathol. 2015): Whole exome sequencing of 12 breast AdCCs
- Authors
- Martelotto, Luciano G.De Filippo, Maria R.Ng, Charlotte K. Y.Natrajan, Rachael17 more author(s)...
- Description
Whole exome sequencing of adenoid cystic carcinomas of the breast, a rare type of triple-negative breast cancer characterized by the presence of the MYB-NFIB fusion gene. This dataset contains visual data summaries and clinical data from 12 patients. Data includes mutation and treatment information, genomic alterations, and data on recurrence and metastasis.
- Subject
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Carcinoma, Adenoid CysticExome SequencingTriple Negative Breast Neoplasms
- Access Rights
- Free to All
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Copper depletion modulates OXPHOS in SOX2/OCT4+ cancer cells to impair triple negative breast cancer metastasis.
- Authors
- Li, ZhuoningMittal, Vivek
- Description
Description from PRIDE: "Copper serves as a co-factor for a host of metalloenzymes that contribute to malignant progression. The orally bioavailable copper chelating agent tetrathiomolybdate (TM) has been associated with a significant survival benefit in high-risk triple negative breast cancer (TNBC) patients. Despite these promising data, the mechanisms by which copper depletion impacts metastasis...
- Subject
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Copper Transport ProteinsMitochondria/metabolismNeoplasm MetastasisProteomicsTriple Negative Breast Neoplasms
- Access Rights
- Free to All
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SA501X4F direct library preparation (DLP) single-cell genomes
- Description
Description from EGA: "Microfluidic direct library preparation (DLP) single-cell whole-genome BAM files for fourth-passage patient-derived primary triple-negative breast cancer xenograft SA501X4F."
- Subject
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Microfluidic Analytical TechniquesSingle-Cell AnalysisTriple Negative Breast NeoplasmsWhole Genome Sequencing
- Access Rights
- Free to All
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SA501X3F direct library preparation (DLP) single-cell genomes
- Description
Description from EGA: "Microfluidic direct library preparation (DLP) single-cell whole-genome BAM files for third-passage patient-derived primary triple-negative breast cancer xenograft SA501X3F."
- Subject
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Microfluidic Analytical TechniquesSingle-Cell AnalysisTriple Negative Breast NeoplasmsWhole Genome Sequencing
- Access Rights
- Free to All
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184-hTERT-L2, SA501X3F, and SA501X4F bulk genomes
- Description
Description from EGA: "Bulk whole-genome BAM files for 184-hTERT-L2, SA501X3F, and SA501X4F."
- Subject
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Epithelial CellsTriple Negative Breast NeoplasmsWhole Genome Sequencing
- Access Rights
- Free to All