PDGFRβ signaling cooperates with β-catenin to modulate c-Abl and biologic behavior of desmoid-type fibromatosis [microarray]

Authors

Crago, Aimee M.

Socci, Nicholas D.

Description

Summary from GEO: "Unsupervised clustering of desmoid tumors and normal mesenchymal tissues was performed using henes associated with HIF1 activity. This accurately distiguished neoplastic tissues from normal controls. The study sought to identify genes differentially expressed in desmoid-type fibromatosis as opposed to normal mesenchymal tissues. We noted that beta-catenin, the central driver in...

Subject

Angiogenesis

beta Catenin

Fibromatosis, Aggressive

Gene Knockdown Techniques

Oligonucleotide Array Sequence Analysis

Access Rights

Free to All