-
Data from: Th2 cytokines inhibit lymphangiogenesis
- Authors
- Savetsky, Ira L.Ghanta, SwapnaGardenier, Jason C.Torrisi, Jeremy S.5 more author(s)...
- Description
Summary from Dryad: "Abstract: Lymphangiogenesis is the process by which new lymphatic vessels grow in response to pathologic stimuli such as wound healing, inflammation, and tumor metastasis. It is well-recognized that growth factors and cytokines regulate lymphangiogenesis by promoting or inhibiting lymphatic endothelial cell (LEC) proliferation, migration and differentiation. Our group has shown...
- Subject
-
Endothelial CellsInterleukin-13interleukin-4LymphangiogenesisTh2 Cells
- Access Rights
- Free to All
-
Transforming Growth Factor-b Suppresses Type 2 Immunity to Cancer
- Authors
- Liu, MingKuo, FengshenLi, Ming O.
- Description
Summary from GEO: "The immune system employs two distinct defense strategies against infections: pathogen elimination typified by type 1 immunity, and pathogen containment exemplified by type 2 immunity concomitant with tissue repair. Akin to infectious diseases, cancer progresses with cancer cell acquisition of microorganism-like behavior propagating at the expense of the host. While immunological...
- Subject
-
CD4-Positive T-Lymphocytesinterleukin-4Th2 CellsTransforming Growth Factor beta
- Access Rights
- Free to All