An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression

Authors

Albanese, Steven Kyle

Parton, Daniel Lawrence

Isik, Mehtap

Rodriguez-Laureano, Lucelenie

7 more author(s)...

Description

Source code, assay data, full expression results for all ABL1 constructs, wild-type kinases, and ABL1 and SRC mutants, plasmid libraries, and other supporting material for the generation of a library of human kinase domain constructs for automated bacterial expression. From the publication abstract, "Kinases play a critical role in cellular signaling and are dysregulated in a number of diseases,...

Subject

Bacteria/metabolism

Binding sites

Escherichia coli/metabolism

Phosphorylation

Protein Structure, Secondary

Protein-Tyrosine Kinases

Proto-Oncogene Proteins c-abl

src-Family Kinases

Access Rights

Free to All

Fee Required