A multivalent signal-transducing model for the DNMT1-mediated maintenance DNA methylation

Authors

Wang, Gang G.

Grimm, Sara A.

Description

Summary from the GEO: "Heterochromatin-specific histone modifications frequently coexist with mammalian DNA methylation to orchestrate a repressive chromatin state. However, it remains elusive how these epigenetic modifications crosstalk. Here, we report that the first bromoadjacent homology (BAH1) domain and the replication foci targeting sequence (RFTS) of maintenance DNA methyltransferase DNMT1...

Subject

DNA (Cytosine-5-)-Methyltransferase 1

DNA Methylation

Heterochromatin

Histone Code

Histones

Access Rights

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