High frequency intestinal microbiota sampling in allogeneic bone marrow transplant patients

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UID: 10377

Publisher(s): Memorial Sloan Kettering Cancer Center

Description: NCBI BioProject collection containing SRA Experiment data and BioSamples resulting from "high frequency intestinal microbiota sampling in allogeneic bone marrow transplant patients, part of a larger systems biology project examining factors that influence antibiotic resistance, with a focus on the pathogens Vancomycin-Resistant Enterococcus and Klebsiella pneumoniae".

Subject of Study

Subject(s)

Access via BioProject
Raw sequence reads
Accession #: PRJNA394877
Access Restrictions: Free to All
Access Instructions: BioProject collection contains links to SRA Experiments and BioSample data. SRA data can be viewed online through NCBI's Sequence Read Archive Run Browser or downloaded in original tar-compressed FASTQ format.
Associated Publications: Kim S, Becattini S, Moody T, et al. Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus. Nature. 2019; 572(7771):665-669.
Data Type: Genomic
Equipment Used: Illumina MiSeq
The MiSeq is an integrated instrument that performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting in a single run.
Software Used: SRA Toolkit
The NCBI SRA Toolkit enables reading ("dumping") of sequencing files from the SRA database and writing ("loading") files into the .sra format.
Dataset Format(s): FASTQ, TAR

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