Pan-Cancer Atlas (PanCanAtlas)
UID: 10404Publisher(s): United States - National Institutes of Health (NIH) - National Cancer Institute (NCI)
- The Pan-Cancer Atlas (PanCanAtlas) initiative aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer Atlas initiative compares the 33 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. The datasets gathered as part of the PanCan Atlas are included in the larger Genomic Data Commons (GDC) repository.