H3K36 methyltransferase SETD2 regulates lymphoid and neural development [RNA-seq]

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UID: 10511

Author(s): Chu, Scott Haihua*, Hatton, Charlie * MSK affiliated

Description: Summary from the GEO: "Transcript analysis of RNA from murine proB cells to determine B cell repertoire and variable gene usage. RNA proB cells (B220+Cd43+IgM-CD25-) sorted from control and Setd2 knockout mice was analyzed for expression and use in the TRUST B/T cell repertoire algorithm."

Subject of Study

Subject(s)

OncoTree Cancer Type(s)

Lymphoid

Access via GEO
Raw and RNA sequencing data.
Accession #: GSE131588

Access via SRA
RNA-Sequence reads for 8 samples.
Accession #: SRP199112

Access via BioProject
Additional information about overall initiative.
Accession #: PRJNA544097
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus, SRA, and BioProject databases provide open access to these files.
Associated Publications: Chu S, Chabon J, Matovina C, et al. Loss of H3K36 methyltransferase Setd2 impairs V(D)J recombination during lymphoid development. iScience. 2020; 23(3):100941.
Data Type: Genomic
Equipment Used: Illumina NextSeq 500
Dataset Format(s): Plain Text, SRA, TAR
Dataset Size: 590.0 Kb (TAR of TXT), SRA broken up into 8 files of 460 Kb - 737Kb.

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