Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection

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UID: 10985

Author(s): Yewdell, William T.*, Smolkin, Ryan*, Belcheva, Kalina T., Chaudhuri, Jayanta* * MSK affiliated

Description: Summary from GEO:

"The goal of this study is to compare the transcriptomes of memory and naïve B cells, and provide a resource for single cell analysis of murine B cells during influenza infection."

Overall design from GEO:

"Standard droplet-based single cell RNA sequencing of naïve and memory B cells done via 10X and analyzed with Seurat."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE181009

Access via BioProject

Accession #: PRJNA750403

Access via SRA

Accession #: SRP330220
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus, BioProject, and SRA databases provide open access to these files.
Associated Publications: Yewdell W, Smolkin R, Belcheva K, Mendoza A, Michaels A, Cols M, Angeletti D, Yewdell J, Chaudhuri J. Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Reports. 2021; 37(6):109961.
Equipment Used: Illumina NextSeq 550
Sequencing and array capabilities for transcriptome, targeted resequencing and genotype sequencing
Dataset Format(s): TSV, TAR, FASTA, MTX
Dataset Size: 41.0 MB (TAR), 1.6 MB (TSV), 40.7 KB (TSV), 272.8 KB (TSV), 41.2 MB (MTX)

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