Validation of dedifferentiated liposarcoma (DDLS) cell lines with the original tumors via copy number alteration analysis [array]

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UID: 11013

Author(s): Okada, Tomoyo*, Gularte-Mérida, Rodrigo*, Shen, Yawei*, Singer, Samuel* * MSK affiliated

Description: Summary from GEO:

"We validated patient's tumor-derived cell lines of liposarcoma by analysing copy number alterations using aCGH or WGS and comparing with the original tumor tissues."

Overall design from GEO:

"Examination of copy number alterations for 2 cell lines, one of the original tumor, one PDX-tumor and its original tumor."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE184701

Access via BioProject

Accession #: PRJNA765693
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus and BioProject databases provide open access to these files.
Associated Publications: Angeles C, Velez A, Rios J, Laxa B, Shum D, Ruiz P, Shen Y, Ostrovnaya I, Gularte-Mérida R, Nacev B, Dickson M, Djaballah H, Okada T, Singer S. A high-content screen for C/EBPα expression identifies novel therapeutic agents in dedifferentiated liposarcoma. Clinical Cancer Research. 2022; 28(1):175-186.
Equipment Used: Agilent-014693 Human Genome CGH Microarray 244A (Feature number version)
high-resolution tool for genome-wide DNA variation profiling without amplification or complexity reduction.
Dataset Format(s): TAR, TXT
Dataset Size: 134.4 MB (TAR), 12.6 KB (TXT)

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