CTLH E3 Ligase Regulates the Degradation of HMG-CoA Synthase 1 Through the Pro/N-end Rule Pathway: MassIVE MSV000090814

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UID: 11479

Author(s): Ordureau, Alban Simon Georges*, An, Heeseon* * MSK affiliated

Description: Description from MassIVE:

"Supporting raw MS data for paper (doi: 10.1016/j.molcel.2024.04.026) by Yi S.A. et al, titled "CTLH E3 Ligase Regulates the Degradation of HMG-CoA Synthase 1 Through the Pro/N-end Rule Pathway". Index of RAW files uploaded: - Related to Supplementary Table 1 (HA-9-81-X | WT (1), ATG7KO (2), RB1CC1 (3): whole proteome (Unimod: 35; 2016; 4)). - Related to Supplementary Table 2 - Proteome (HA-1-50: whole proteome (Unimod: 35; 2016; 4)). - Related to Supplementary Table 2 - PhosphoSites (HA-1-50_Phos: phospho proteome (Unimod: 35; 21; 2016; 4)) - Related to Supplementary Table 3 (Yis-1-49: whole proteome (Unimod: 35; 2016; 4))"

Subject of Study

Subject(s)

Access via MassIVE

Accession #: MSV000090814
Access Restrictions: Free to All
Access Instructions: Public access dataset available under a CC0 1.0 Universal (CC0 1.0) license
DOI: 10.25345/C5Q52FJ1J
Associated Publications: Yi S, Sepic S, Schulman B, Ordureau A, An H. mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway. Molecular Cell. 2024; 84(11):2166-2184.e9.
Equipment Used: Orbitrap Eclipse
Mass spectrometer
Dataset Format(s): mzML
Dataset Size: 138.99 GB