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Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients
- Authors
- Nguyen, Bastien
- Description
Description from Zenodo: "Metastatic progression is the main cause of death in cancer patients, whereas the underlying genomic mechanisms driving metastasis remain largely unknown. Here, we assembled MSK-MET, a pan-cancer cohort of over 25,000 patients with metastatic diseases. By analyzing genomic and clinical data from this cohort, we identified associations between genomic alterations and patterns...
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Chromosomal InstabilityGenomicsMutationNeoplasm MetastasisSequence Analysis, DNA
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MSK MetTropism (MSK, Cell 2021)
- Authors
- Nguyen, BastienFong, ChristopherLuthra, AnishaSmith, Shaleigh A.71 more author(s)...
- Description
Description from cBioPortal: "MSK-MET (Memorial Sloan Kettering - Metastatic Events and Tropisms) is an integrated pan-cancer cohort of tumor genomic and clinical outcome data from 25,000 patients. We analyzed this dataset to identify associations between tumor genomic alterations and patterns of metastatic dissemination across 50 tumor types. We found that chromosomal instability is strongly correlated...
- Subject
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Adenocarcinoma of LungCarcinoma, Ductal, BreastChromosomal InstabilityGenomicsNeoplasm MetastasisProstatic Neoplasms
- Access Rights
- Free to All
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Organ Site Mapping for Metastatic Cancer
- Authors
- DiNatale, Renzo G.Fong, Christopher
- Description
Description from GitHub: "Cancer is a disease that can involve metastatic spread from it primary site (Ex. Lung) to another organ (Ex. Liver). However, the naming conventions used for this organs can slightly vary, or may be specified with more granularity than commonly appropriate. This is evident in free text entries, where the variability is large. This repository contains functions that will...
- Subject
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Biological OntologiesData CurationNeoplasm MetastasisOrgan Specificity
- Access Rights
- Free to All