-
SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...
- Subject
-
Breast NeoplasmsCarcinoma, HepatocellularCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellColorectal NeoplasmsDNA Mutational AnalysisEndometrial NeoplasmsEsophageal NeoplasmsGenes, erbBGenes, erbB-2MelanomaOvarian NeoplasmsPancreatic NeoplasmsSalivary Gland NeoplasmsSarcomaSkin NeoplasmsUrinary Bladder NeoplasmsUterine Cervical Neoplasms
- Access Rights
- Free to All
-
TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...
- Subject
-
DNA Mutational AnalysisImmunotherapyMutationTumor Burden
- Access Rights
- Free to All
-
Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal
- Description
This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...
- Subject
-
AdenocarcinomaAdenocarcinoma of LungBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, NeuroendocrineCarcinoma, Renal CellCarcinoma, Squamous CellCell-Free Nucleic AcidsChoriocarcinomaEndodermal Sinus TumorMelanomaNeoplasms, Germ Cell and EmbryonalNeoplasms, Squamous CellNeuroendocrine TumorsProstatic NeoplasmsSeminomaSmall Cell Lung CarcinomaUrinary Bladder Neoplasms
- Access Rights
- Free to All