This dataset contains summary data visualizations and clinical data of rectal cancer tumoroids based on massively parallel sequencing using the custom, Food and Drug Administration (FDA)-cleared tumor-profiling panel MSK Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT). The clinical data includes mutation count, information about mutated genes, Gene Panel, Impact TMB Score,...

Author summary from Gene Expression Omnibus: "Assaying binding of REST to DNA with ChIP-seq reveals the role of REST in transcriptional regulation in colorectal cancer (CRC) metastatic stem cells (MetSCs). REST is especially relevant to regulation of L1CAM expression." Overall Design: "ChIP-seq of binding of REST to DNA." Abstract summary: "Metastasis-initiating cells with stem-like properties drive...

Dataset Summary Description: "The Angiosarcoma Project is an ongoing patient-driven initiative. This archived Angiosarcoma Project dataset was analyzed in the linked Nature Medicine 2020 manuscript, and is derived from 48 samples from 36 angiosarcoma patients. Angiosarcoma tumor specimens (FFPE) were subjected to whole-exome sequencing (along with matched germline whole-exome sequencing). In addition...

Dataset Summary Description: "This provisional dataset is currently derived from 83 samples, including tumor specimens (FFPE and cfDNA) from 62 angiosarcoma patients subjected to WES (along with matched germline WES). This study includes genomic data, patient-reported data (pre-pended as PRD), medical record data (MedR), and pathology report data (PATH). As these data were generated in a research...

This dataset contains the summary data visualizations and clinical data from targeted sequencing of 1,099 metastatic colorectal tumor/normal pairs from 1,134 patients. Clinical data includes: Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Overall Survival Status, Sample Type, Sex, Age at Diagnosis, Chemo Exposure of sequenced specimen, First Site of Metastasis, Gene Panel,...