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Clinical Proteomic Tumor Analysis Consortium Data
- Alternate Title(s)
- CPTAC
- Description
The Clinical Proteomic Tumor Analysis Consortium (CPTAC) analyzes cancer biospecimens by mass spectrometry, characterizing and quantifying their constituent proteins, or proteome. Proteomic analysis for each CPTAC study is carried out independently by Proteomic Characterization Centers (PCCs) using a variety of protein fractionation techniques, instrumentation, and workflows. Mass spectrometry and...
- Subject
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Chemical fractionationGenomicsMass spectrometryProteome
- Access Rights
- Free to All
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Colorectal Adenocarcinoma (TCGA, PanCancer Atlas) data
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 594 colorectal adenocarcinomas from 594 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
- Subject
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Adenocarcinoma, MucinousColonic NeoplasmsColorectal NeoplasmsDNA Mutational AnalysisRectal Neoplasms
- Access Rights
- Free to All
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SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...
- Subject
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Breast NeoplasmsCarcinoma, HepatocellularCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellColorectal NeoplasmsDNA Mutational AnalysisEndometrial NeoplasmsEsophageal NeoplasmsGenes, erbBGenes, erbB-2MelanomaOvarian NeoplasmsPancreatic NeoplasmsSalivary Gland NeoplasmsSarcomaSkin NeoplasmsUrinary Bladder NeoplasmsUterine Cervical Neoplasms
- Access Rights
- Free to All
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Tumors with TRK fusions (MSK, 2019): Tumors with TRK fusions based on MSK-IMPACT targeted sequencing.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of tropomyosin receptor kinase (TRK) fusion tumors. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), information about mutated genes, patient demographics, and modality. The data set also...
- Subject
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DNA Mutational AnalysisOncogene Proteins, FusionReceptor Protein-Tyrosine KinasesReceptor, trkAReceptor, trkBReceptor, trkC
- Access Rights
- Free to All
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TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...
- Subject
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DNA Mutational AnalysisImmunotherapyMutationTumor Burden
- Access Rights
- Free to All