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  • MSK MetTropism (MSK, Cell 2021)

    Authors
    Nguyen, Bastien
    Fong, Christopher
    Luthra, Anisha
    Smith, Shaleigh A.
    71 more author(s)...
    Description

    Description from cBioPortal: "MSK-MET (Memorial Sloan Kettering - Metastatic Events and Tropisms) is an integrated pan-cancer cohort of tumor genomic and clinical outcome data from 25,000 patients. We analyzed this dataset to identify associations between tumor genomic alterations and patterns of metastatic dissemination across 50 tumor types. We found that chromosomal instability is strongly correlated...

    Subject
    Adenocarcinoma of Lung
    Carcinoma, Ductal, Breast
    Chromosomal Instability
    Genomics
    Neoplasm Metastasis
    Prostatic Neoplasms
    Access Rights
    Free to All
  • Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

    Authors
    Nguyen, Bastien
    Description

    Description from Zenodo: "Metastatic progression is the main cause of death in cancer patients, whereas the underlying genomic mechanisms driving metastasis remain largely unknown. Here, we assembled MSK-MET, a pan-cancer cohort of over 25,000 patients with metastatic diseases. By analyzing genomic and clinical data from this cohort, we identified associations between genomic alterations and patterns...

    Subject
    Chromosomal Instability
    Genomics
    Mutation
    Neoplasm Metastasis
    Sequence Analysis, DNA