-
TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...
- Subject
-
DNA Mutational AnalysisImmunotherapyMutationTumor Burden
- Access Rights
- Free to All
-
Patient-Derived Nasopharyngeal Cancer Organoids for Disease Modelling and Radiation Dose Optimization
- Authors
- Sasidharan, Lucky S.Tan, Min H.
- Description
Summary from the GEO: "Background: Effective radiation treatment (RT) for recurrent nasopharyngeal cancers (NPC), featuring an intrinsic hypoxic sub-volume, remains a clinical challenge. Lack of disease‐specific in-vitro models, together with difficulties in establishing patient derived xenograft (PDX) models, have further hindered development of personalized therapeutic options. Methods: Here in,...
- Subject
-
Nasopharyngeal NeoplasmsOrganoids
- Access Rights
- Free to All