14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis

Authors

Fu, Wenyu

Hettinghouse, Aubryanna

Hu, Wenhuo

Liu, Chuan-Ju

Description

Summary from GEO: "In an effort to identify novel differentially-expressed genes in OA, we performed RNA-seq analysis using cartilage isolated from nonarthritic and OA patients. Total RNA was isolated from 3 samples of nonarthritic cartilage and 4 samples of OA cartilage (Kellgren-Lawrence Grade 3 or 4). Genes (900 total, 600 up-regulated, 300 down-regulated) were differentially expressed in OA vs....

Subject

14-3-3 Proteins

Gene Expression Profiling

MicroRNAs

Osteoarthritis

Receptors, Tumor Necrosis Factor, Type II

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