Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

Authors

Tuveson, David

Robson, Paul

Elyada, Ela

Bolisetty, Mohan

18 more author(s)...

Description

Description from dbGaP: "Cancer-associated fibroblasts (CAFs) are major players in the progression and drug resistance of pancreatic ductal adenocarcinoma (PDAC). CAFs constitute a diverse cell population consisting of several recently described subtypes, although the extent of CAF heterogeneity has remained undefined. Here we employ single-cell RNA-sequencing to thoroughly characterize the neoplastic...

Subject

Cancer-Associated Fibroblasts

Carcinoma, Pancreatic Ductal

Epithelial Cells

RNA-Seq

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