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Results Found: 2
  • The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma

    Authors
    Polaski, Jacob T.
    Kannan, Ram
    Bradley, Robert K.
    Description

    Summary from the GEO: "Pancreatic adenosquamous carcinoma (PASC) is an aggressive cancer whose mutational origins are poorly understood. An early study reported high-frequency somatic mutations affecting UPF1, a core nonsense-mediated mRNA decay (NMD) factor, in PASC, but subsequent studies did not observe these lesions. The corresponding controversy about whether UPF1 mutations are important contributors...

    Subject
    Carcinoma, Adenosquamous
    Pancreatic Neoplasms
    RNA Helicases
    Trans-Activators
    Access Rights
    Free to All
  • Pancreatic ductal adenocarcinoma and panreatic adenosquamous carcinoma sequencing

    Description

    Description from the BioProject: "In this study, whole genome sequencing and whole exome sequencing were performed to detect the genomic features of the pancreatic adenosquamous carcinoma." 125 samples were deposited and sequenced in this submission.

    Subject
    Carcinoma, Adenosquamous
    Pancreatic Neoplasms
    Access Rights
    Free to All