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Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal
- Description
This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...
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AdenocarcinomaAdenocarcinoma of LungBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, NeuroendocrineCarcinoma, Renal CellCarcinoma, Squamous CellCell-Free Nucleic AcidsChoriocarcinomaEndodermal Sinus TumorMelanomaNeoplasms, Germ Cell and EmbryonalNeoplasms, Squamous CellNeuroendocrine TumorsProstatic NeoplasmsSeminomaSmall Cell Lung CarcinomaUrinary Bladder Neoplasms
- Access Rights
- Free to All
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Mixed cfDNA (MSK, Nature Medicine 2019): Targeted sequencing of 248 samples from 124 patients' cfDNA/WBC and tumor/normal pairs.
- Description
This dataset contains the summary data visualizations and clinical data of targeted sequencing of 248 samples from 124 patients' cfDNA/WBC[White Blood Cell] and tumor/normal pairs. Clinical data includes: Cancer Type, Mutation Count, Age, Tumor Type, cfDNA TMB, Collapsed fragment mean coverage, Collapsed mean coverage, ctDNA Fraction, MSI Score, Oncotree Code, cfDNA/Tumor Sample Class, Tumor Tissue...
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Breast NeoplasmsCarcinoma, Non-Small-Cell LungCell-Free Nucleic AcidsProstatic Neoplasms
- Access Rights
- Free to All
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Tumor Fraction Guided Cell-Free DNA Profiling in Metastatic Cancer Patients
- Authors
- Solit, DavidTsui, Wai Yi
- Description
Study Description from daGaP: "Cell-free DNA (cfDNA) profiling is increasingly used to guide cancer care, yet mutations are not always identified. The ability to detect somatic mutations in plasma depends on both assay sensitivity and the fraction of circulating DNA in plasma that is tumor-derived (i.e cfDNA tumor fraction). We hypothesized that cfDNA tumor fraction could inform the interpretation...
- Subject
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Cell-Free Nucleic AcidsDNA Mutational Analysis
- Access Rights
- Application Required