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Colorectal Adenocarcinoma (TCGA, PanCancer Atlas) data
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 594 colorectal adenocarcinomas from 594 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
- Subject
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Adenocarcinoma, MucinousColonic NeoplasmsColorectal NeoplasmsDNA Mutational AnalysisRectal Neoplasms
- Access Rights
- Free to All
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MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay
- Description
This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...
- Subject
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AdenocarcinomaAdenocarcinoma of LungAdenocarcinoma, MucinousBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, HepatocellularCarcinoma, LobularCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellCarcinoma, Squamous CellCarcinosarcomaCholangiocarcinomaColonic NeoplasmsColorectal NeoplasmsCystadenocarcinoma, SerousDNA Mutational AnalysisGallbladder NeoplasmsGlioblastomaLiposarcomaLung NeoplasmsLymphoma, FollicularMelanomaMesotheliomaNeoplasms, Squamous CellNeurofibromaOligodendrogliomaOsteosarcomaOvarian NeoplasmsPancreatic NeoplasmsProstatic NeoplasmsRectal NeoplasmsSarcomaSarcoma, SynovialSquamous Cell Carcinoma of Head and NeckStomach NeoplasmsThyroid Cancer, PapillaryUrinary Bladder NeoplasmsUterine NeoplasmsUveal Neoplasms
- Access Rights
- Free to All
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SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...
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Breast NeoplasmsCarcinoma, HepatocellularCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellColorectal NeoplasmsDNA Mutational AnalysisEndometrial NeoplasmsEsophageal NeoplasmsGenes, erbBGenes, erbB-2MelanomaOvarian NeoplasmsPancreatic NeoplasmsSalivary Gland NeoplasmsSarcomaSkin NeoplasmsUrinary Bladder NeoplasmsUterine Cervical Neoplasms
- Access Rights
- Free to All
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NCI-60 Cell Lines (NCI, Cancer Res 2012): Whole-exome sequencing of 67 samples by NCI-60 cell line project
- Description
This dataset contains summary data visualizations and clinical data from 67 samples from 67 patients as part an NCI-60 cell line project to compile NCI-60 cell line high-throughput and high-content data into CellMiner, a genomic and pharmacologic database created by the National Cancer Center Institute. The clinical data includes deidentified patient and sample IDs, mutation counts, detailed cancer...
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AdenocarcinomaBrain NeoplasmsBreast NeoplasmsCarcinoma, Renal CellColorectal NeoplasmsDNA Mutational AnalysisLeukemia, MyeloidLung NeoplasmsMelanomaOvarian NeoplasmsProstatic Neoplasms
- Access Rights
- Free to All
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Colorectal Adenocaranoma (TCGA, Firehose Legacy)
- Description
TCGA Colorectal Adenocarcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 640 carcinomas from 636 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...
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AdenocarcinomaColorectal NeoplasmsDNA Mutational Analysis
- Access Rights
- Free to All
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Regenerative origin of metastasis stem cells
- Authors
- Ganesh, KarunaMassagué, JoanKoche, Richard PatrickReuter, Vincent Patrick
- Description
Author summary from Gene Expression Omnibus: "Assaying binding of REST to DNA with ChIP-seq reveals the role of REST in transcriptional regulation in colorectal cancer (CRC) metastatic stem cells (MetSCs). REST is especially relevant to regulation of L1CAM expression." Overall Design: "ChIP-seq of binding of REST to DNA." Abstract summary: "Metastasis-initiating cells with stem-like properties drive...
- Subject
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Colorectal NeoplasmsNeoplastic Stem Cells
- Access Rights
- Free to All
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The Angiosarcoma Project (Provisional): an ongoing patient-driven initiative.
- Description
Dataset Summary Description: "This provisional dataset is currently derived from 83 samples, including tumor specimens (FFPE and cfDNA) from 62 angiosarcoma patients subjected to WES (along with matched germline WES). This study includes genomic data, patient-reported data (pre-pended as PRD), medical record data (MedR), and pathology report data (PATH). As these data were generated in a research...
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Basal Cell CarcinomaBreast NeoplasmsColorectal NeoplasmsHemangiosarcomaHodgkin DiseaseLeukemia, Lymphocytic, Chronic, B-CellProstatic NeoplasmsRectal NeoplasmsSkin NeoplasmsThyroid NeoplasmsUterine NeoplasmsVulvar Neoplasms
- Access Rights
- Free to All
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Metastatic Colorectal Cancer (MSKCC, Cancer Cell 2018): Targeted sequencing of 1,134 metastatic colorectal tumor/normal pairs.
- Description
This dataset contains the summary data visualizations and clinical data from targeted sequencing of 1,099 metastatic colorectal tumor/normal pairs from 1,134 patients. Clinical data includes: Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Overall Survival Status, Sample Type, Sex, Age at Diagnosis, Chemo Exposure of sequenced specimen, First Site of Metastasis, Gene Panel,...
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Colonic NeoplasmsColorectal Neoplasms
- Access Rights
- Free to All
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Global proteome analysis of paired colorectal cancer sample using LC-MS/MS
- Authors
- Tanaka, AtsushiRoehrl, Michael H.
- Description
Description from PRIDE: "To find differentially expressed protein in colorectal cancer compared with normal colon tissue, we performed global proteome analysis using LC-MS."
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Biomarkers, TumorColorectal NeoplasmsLiquid Chromatography-Mass SpectrometryMucous MembraneProlyl HydroxylasesSurvival Analysis
- Access Rights
- Free to All
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Colorectal cancer proteome project for biomarke search and development of clinical test
- Authors
- Tanaka, AtsushiRoehrl, Michael H.
- Description
Description from PRIDE: "To find differentially expressed protein in colorectal cancer compared with normal colon tissue, we performed global proteome analysis using LC-MS."
- Subject
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Biomarkers, TumorColorectal NeoplasmsLiquid Chromatography-Mass SpectrometryProteome
- Access Rights
- Free to All