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  • The emergent landscape of the mouse gut endoderm at single-cell resolution [scRNA-seq]

    Authors
    Nowotschin, Sonja
    Kuo, Ying-Yi
    Liu, Vincent
    Garg, Vidur
    10 more author(s)...
    Description

    Summary from GEO: "To comprehensively delineate the ontogeny of an organ system, we generated 112,217 single- cell transcriptomes representing all endoderm populations within the mouse embryo until midgestation. We employed graph-based approaches to model differentiating cells for spatio- temporal characterization of developmental trajectories. Our analysis reveals the detailed architecture of the...

    Subject
    Cell Differentiation
    Endoderm
    Single-Cell Analysis
    Transcriptome
    Access Rights
    Free to All
  • The emergent landscape of the mouse gut endoderm at single-cell resolution [RNA-seq]

    Authors
    Nowotschin, Sonja
    Setty, Manu
    Kuo, Ying-Yi
    Liu, Vincent
    10 more author(s)...
    Description

    Summary from GEO: "To comprehensively delineate the ontogeny of an organ system, we generated 112,217 single- cell transcriptomes representing all endoderm populations within the mouse embryo until midgestation. We employed graph-based approaches to model differentiating cells for spatio- temporal characterization of developmental trajectories. Our analysis reveals the detailed architecture of the...

    Subject
    Endoderm
    RNA-Seq
    Single-Cell Analysis
    Transcriptome
    Access Rights
    Free to All
  • Pharyngeal endoderm development

    Authors
    Weiler, Philipp
    Lange, Marius
    Klein, Michal
    Description

    Description from Figshare: "AnnData object of scRNA-seq dataset of pharyngeal endoderm development data." DOI corresponds to the Figshare data collection to which this dataset belongs

    Subject
    Endoderm
    Pharynx
    RNA-Seq
    Sequence Analysis, RNA
    Single-Cell Analysis
    Access Rights
    Free to All
  • Single-cell mapping of lineage and identity in direct reprogramming

    Authors
    Biddy, Brent A.
    Morris, Samantha A.
    Description

    Description from GEO: "Direct lineage reprogramming involves the conversion of cellular identity. Single-cell technologies are useful for deconstructing the considerable heterogeneity that emerges during lineage conversion. However, lineage relationships are typically lost during cell processing, complicating trajectory reconstruction. Here we present ‘CellTagging’, a combinatorial cell-indexing...

    Subject
    Cell Lineage
    Endoderm
    Genomics
    Methyltransferases
    Single-Cell Analysis
    Access Rights
    Free to All
  • MEF to induced endoderm progenitors reprogramming

    Authors
    Lange, Marius
    Klein, Michal
    Description

    Description from Figshare: "scRNA-seq time-series dataset of mouse embryonic fibroblast (MEF) reprogramming to induced endoderm progenitors (iEPs) assayed using Dropseq and 10x Genomics. Contains 8 time points spanning days 0-28 during reprogramming. Total cell number is 104,887. This dataset contains raw spliced and unspliced counts estimated using the velocyto pipeline (La Manno et al., Nature...

    Subject
    Endoderm
    Fibroblasts
    RNA-Seq
    Single-Cell Gene Expression Analysis
    Access Rights
    Free to All