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The emergent landscape of the mouse gut endoderm at single-cell resolution [scRNA-seq]
- Authors
- Nowotschin, SonjaKuo, Ying-YiLiu, VincentGarg, Vidur10 more author(s)...
- Description
Summary from GEO: "To comprehensively delineate the ontogeny of an organ system, we generated 112,217 single- cell transcriptomes representing all endoderm populations within the mouse embryo until midgestation. We employed graph-based approaches to model differentiating cells for spatio- temporal characterization of developmental trajectories. Our analysis reveals the detailed architecture of the...
- Subject
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Cell DifferentiationEndodermSingle-Cell AnalysisTranscriptome
- Access Rights
- Free to All
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The emergent landscape of the mouse gut endoderm at single-cell resolution [RNA-seq]
- Authors
- Nowotschin, SonjaSetty, ManuKuo, Ying-YiLiu, Vincent10 more author(s)...
- Description
Summary from GEO: "To comprehensively delineate the ontogeny of an organ system, we generated 112,217 single- cell transcriptomes representing all endoderm populations within the mouse embryo until midgestation. We employed graph-based approaches to model differentiating cells for spatio- temporal characterization of developmental trajectories. Our analysis reveals the detailed architecture of the...
- Subject
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EndodermRNA-SeqSingle-Cell AnalysisTranscriptome
- Access Rights
- Free to All
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Pharyngeal endoderm development
- Authors
- Weiler, PhilippLange, MariusKlein, Michal
- Description
Description from Figshare: "AnnData object of scRNA-seq dataset of pharyngeal endoderm development data." DOI corresponds to the Figshare data collection to which this dataset belongs
- Subject
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EndodermPharynxRNA-SeqSequence Analysis, RNASingle-Cell Analysis
- Access Rights
- Free to All
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Single-cell mapping of lineage and identity in direct reprogramming
- Authors
- Biddy, Brent A.Morris, Samantha A.
- Description
Description from GEO: "Direct lineage reprogramming involves the conversion of cellular identity. Single-cell technologies are useful for deconstructing the considerable heterogeneity that emerges during lineage conversion. However, lineage relationships are typically lost during cell processing, complicating trajectory reconstruction. Here we present ‘CellTagging’, a combinatorial cell-indexing...
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Cell LineageEndodermGenomicsMethyltransferasesSingle-Cell Analysis
- Access Rights
- Free to All
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MEF to induced endoderm progenitors reprogramming
- Authors
- Lange, MariusKlein, Michal
- Description
Description from Figshare: "scRNA-seq time-series dataset of mouse embryonic fibroblast (MEF) reprogramming to induced endoderm progenitors (iEPs) assayed using Dropseq and 10x Genomics. Contains 8 time points spanning days 0-28 during reprogramming. Total cell number is 104,887. This dataset contains raw spliced and unspliced counts estimated using the velocyto pipeline (La Manno et al., Nature...
- Subject
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EndodermFibroblastsRNA-SeqSingle-Cell Gene Expression Analysis
- Access Rights
- Free to All