Study Description from dbGaP:"Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) was one of five projects funded in 2010 as part of the NCI's Genetic Associations and Mechanisms in Oncology (GAME-ON) initiative (http://epi.grants.cancer.gov/gameon/). GAME-ON's overall goal was to foster an intra-disciplinary and collaborative approach to the translation of promising research...

Study Description from dbGaP: "The data come from 40 studies participating in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). CIMBA recruits individuals with pathogenic mutations in BRCA1 or BRCA2. The majority of carriers were recruited through cancer genetics clinics offering genetic testing, and were enrolled into national or regional studies. The remainder were identified by population-based...

Description from Figshare: "Table S1. List of MH258 chromosomal essential genes as identified by the EL-ARTIST pipeline (19). For the sliding window analysis, 1000 simulations, window size of 10, and p-value of 0.05 were used. 1, non-essential; 2, essential; 3, domain essential. Table S2. Mutants with enhanced fitness in gut colonization. Ratios of the read counts to the total read counts are listed...