Discovery of a Drug Candidate for GLIS3-Associated Diabetes

Authors

Amin, Sadaf

Cook, Brandoch

Zhou, Ting

Ghazizadeh, Zaniar

13 more author(s)...

Description

Comparison of WT and GLIS3-/- cells at various stages of human pancreatic differentiation. From Gene Expression Omnibus authors' summary: "Through development and use of a minimal component protocol for derivation of late stage pancreatic progenitors and beta-like cells, we compared WT and GLIS3-/- pancreatic cells at different stages and discovered that GLIS3-/- cells show an ectopic activation...

Subject

Cell Differentiation/genetics

Diabetes Mellitus

Human Embryonic Stem Cells

Hypoglycemic Agents

Insulin-Secreting Cells

Transcription Factors

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