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Results Found: 3
  • Genetic ancestry effects on the response to viral infection are pervasive but cell type specific

    Authors
    Randolph, Haley E.
    Description

    Description from BioProject: "Humans differ in their susceptibility to infectious disease, partly due to variation in the immune response following infection. We used single-cell RNA-sequencing to quantify variation in the response to influenza infection in peripheral blood mononuclear cells from European- and African-ancestry males. Genetic ancestry effects are common but highly cell type-specific....

    Subject
    Immunity, Active
    Influenza, Human
    Interferon Type I
    Single-Cell Gene Expression Analysis
    Viral Infections
    Access Rights
    Free to All
  • Influenza A response variation scripts

    Authors
    Randolph, Haley E.
    Description

    Description from Zenodo: "Input files and scripts to run the main analyses for influenza A virus (IAV) response variation project. The pipeline is published on GitHub as "IAV_population-variation" (https://github.com/herandolph/IAV_population-variation). " Description from GitHub: "code necessary to reproduce the main analyses published in: Genetic ancestry effects on the response to viral infection...

    Subject
    Immunity, Active
    Influenza A virus
    Viral Infections
    Access Rights
    Free to All
  • hla2023

    Authors
    Kang, Joyce
    Description

    Description from GitHub and Zenodo: "Code for mapping single-cell eQTLs for HLA genes across four cohorts"

    Subject
    Genomics
    HLA Antigens
    Immunity, Active
    Quantitative Trait Loci
    Single-Cell Analysis
    Access Rights
    Free to All