Divergent role for STAT5 in the adaptive responses of natural killer cells

Authors

Lau, Colleen M.

Sun, Joseph C.

Description

Summary from the GEO: "Natural killer (NK) cells are innate lymphocytes with the capacity to elicit adaptive features, including clonal expansion and immunological memory. Because signal transducer and activator of transcription 5 (STAT5) is essential for NK cell development, the role of this transcription factor and its upstream cytokines IL-2 and IL-15 during infection have not been carefully investigated....

Subject

Cytokines

Immunologic Memory

Interleukin-15

Interleukin-2

Killer Cells, Natural

STAT5 Transcription Factor

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