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  • Divergent role for STAT5 in the adaptive responses of natural killer cells

    Authors
    Lau, Colleen M.
    Sun, Joseph C.
    Description

    Summary from the GEO: "Natural killer (NK) cells are innate lymphocytes with the capacity to elicit adaptive features, including clonal expansion and immunological memory. Because signal transducer and activator of transcription 5 (STAT5) is essential for NK cell development, the role of this transcription factor and its upstream cytokines IL-2 and IL-15 during infection have not been carefully investigated....

    Subject
    Cytokines
    Immunologic Memory
    Interleukin-15
    Interleukin-2
    Killer Cells, Natural
    STAT5 Transcription Factor
    Access Rights
    Free to All
  • Tumor MHC Class I Expression Associates with Interleukin-2 Response in Melanoma (raw data)

    Authors
    Pourmaleki, Maryam
    Jones, Caitlin J.
    Ariyan, Charlotte Eielson
    Zeng, Zheng
    28 more author(s)...
    Description

    Raw data (multiplexed IF and NanoString) supporting the findings of the publication "Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma." The processed multiplexed IF data and sample ID key are available at (https://zenodo.org/record/7627120). All code used to produce the results of this study are available at https://github.com/cBio-MSKCC/Halo_Melanoma_IL2. Note:...

    Subject
    Immunotherapy
    Interleukin-2
    Melanoma
    Microscopy, Fluorescence
    Tumor Microenvironment
    Access Rights
    Free to All
  • Tumor MHC Class I Expression Associates with Interleukin-2 Response in Melanoma (processed data)

    Authors
    Pourmaleki, Maryam
    Jones, Caitlin J.
    Ariyan, Charlotte Eielson
    Zeng, Zheng
    28 more author(s)...
    Description

    Description from Zenodo: "The processed multiplexed IF data and sample ID corresponding to the raw data in record (https://zenodo.org/record/4300912#.Y-WGBuzMKY-). All code used to produce the results of this study are available at https://github.com/cBio-MSKCC/Halo_Melanoma_IL2." Note: The GitHub link provided by the dataset creators no longer works.

    Subject
    Immunotherapy
    Interleukin-2
    Melanoma
    Microscopy, Fluorescence
    Tumor Microenvironment
    Access Rights
    Free to All