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Divergent role for STAT5 in the adaptive responses of natural killer cells
- Authors
- Lau, Colleen M.Sun, Joseph C.
- Description
Summary from the GEO: "Natural killer (NK) cells are innate lymphocytes with the capacity to elicit adaptive features, including clonal expansion and immunological memory. Because signal transducer and activator of transcription 5 (STAT5) is essential for NK cell development, the role of this transcription factor and its upstream cytokines IL-2 and IL-15 during infection have not been carefully investigated....
- Subject
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CytokinesImmunologic MemoryInterleukin-15Interleukin-2Killer Cells, NaturalSTAT5 Transcription Factor
- Access Rights
- Free to All
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Tumor MHC Class I Expression Associates with Interleukin-2 Response in Melanoma (raw data)
- Authors
- Pourmaleki, MaryamJones, Caitlin J.Ariyan, Charlotte EielsonZeng, Zheng28 more author(s)...
- Description
Raw data (multiplexed IF and NanoString) supporting the findings of the publication "Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma." The processed multiplexed IF data and sample ID key are available at (https://zenodo.org/record/7627120). All code used to produce the results of this study are available at https://github.com/cBio-MSKCC/Halo_Melanoma_IL2. Note:...
- Subject
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ImmunotherapyInterleukin-2MelanomaMicroscopy, FluorescenceTumor Microenvironment
- Access Rights
- Free to All
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Tumor MHC Class I Expression Associates with Interleukin-2 Response in Melanoma (processed data)
- Authors
- Pourmaleki, MaryamJones, Caitlin J.Ariyan, Charlotte EielsonZeng, Zheng28 more author(s)...
- Description
Description from Zenodo: "The processed multiplexed IF data and sample ID corresponding to the raw data in record (https://zenodo.org/record/4300912#.Y-WGBuzMKY-). All code used to produce the results of this study are available at https://github.com/cBio-MSKCC/Halo_Melanoma_IL2." Note: The GitHub link provided by the dataset creators no longer works.
- Subject
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ImmunotherapyInterleukin-2MelanomaMicroscopy, FluorescenceTumor Microenvironment
- Access Rights
- Free to All