This dataset contains summary data visualizations and clinical data from a broad sampling of hepatocellular adenomas and carcinomas. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), Patient ID, Sample ID, Cancer Type Detailed, Mutation Count, Fraction Genome Altered, Collaboration...

This dataset contains summary data visualizations and clinical data from a broad sampling of hepatocellular carcinomas. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes mutation count, information about mutated genes, patient demographics, modality details, and disease status. The data set also includes copy-number segment data downloadable as .seg...

TCGA Liver Hepatocellular Carcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 442 carcinomas from 440 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...

This dataset contains summary data visualizations and clinical data from a broad sampling of 412 intrahepatic cholangiocarcinomas from 412 patients. The clinical data includes mutation count, information about mutated genes, patient demographics, adjuvant chemotherapy, patient BMI, Duct Type, DZ Extent, CA19, CA19 High, and presence of chronic viral hepatitis, cirrhosis, diabetes, ECOG BIN, HAIC,...

This dataset contains summary data visualizations and clinical data from a sampling of 219 intrahepatic cholangiocarcinomas from 219 patients. The clinical data includes mutation count, presence of an Archer Panel, MSK IMPACT TMB Percentiles across & within tumor types, Metastatic Sites and the availability of MSK Pathology slide, Mutation Count, Age at Which Sequencing was Reported, Archer Panel,...

Study Description from dbGaP: "Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare liver tumor primarily affecting adolescents and young adults. Little is known of the molecular pathogenesis. To characterize the disease we performed RNA sequencing and whole genome sequencing on FL-HCC tumors and adjacent normal tissue. The results demonstrate few consistent differences on the chromosomal level...

Summary from GEO: "Large-scale genome sequencing efforts of human tumors identified epigenetic modifiers as one of the most frequently mutated gene class in human cancer. However, how these mutations drive tumor development and progression is largely unknown. Here, we identify the histone demethylase KDM6A as an important tumor suppressor in solid cancers, such as liver cancer and pancreatic cancer....

Characterization of the surface proteome changes between proliferating and senescent liver cancer cells induced by p53 restoration.