Lobular Carcinomas In Situ Display Intra-Lesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Disease

Authors

King, Tari A.

Reis-Filho, Jorge S.

Description

Description from dbGaP: "This study comprises prospectively accrued, microdissected fresh frozen samples of multifocal lobular carcinoma in situ (LCIS), ductal carcinoma in situ (DCIS), invasive lobular carcinoma and invasive ductal carcinoma from patients undergoing prophylactic or therapeutic mastectomies after a diagnosis on LCIS diagnosed and managed at Memorial Sloan Kettering Cancer Center...

Subject

Carcinoma, Ductal, Breast

Carcinoma, Lobular

Exome Sequencing

Mastectomy

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