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Spatiotemporal coordination at the maternal-fetal interface promotes trophoblast invasion and vascular remodeling in the first half of human pregnancy
- Authors
- Angelo, MichaelGreenbaum, ShirleyVan Valen, DavidJaswa, Eleni G.9 more author(s)...
- Description
Description from HuBMAP: "Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels left with a thin, discontinuous smooth muscle layer and partially lined with EVTs. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote...
- Subject
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ArteriesExtravillous TrophoblastsMass spectrometryMaternal-Fetal ExchangePlacentaVolume Electron Microscopy
- Access Rights
- Free to all with registration
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A spatially resolved timeline of the human maternal-fetal interface (tissue block images)
- Authors
- Soon, Erin
- Description
Description from Dryad: "Beginning in the first trimester, fetally-derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote a tissue microenvironment conducive to spiral artery remodeling (SAR). However,...
- Subject
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Extravillous TrophoblastsMaternal-Fetal ExchangeMultiomics
- Access Rights
- Free to All
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A spatially resolved timeline of the human maternal-fetal interface
- Authors
- Averbukh, InnaSoon, Erin
- Description
Description from Figshare: "Files Provided: - denoised.zip,denoised1.zip: denoised MIBI images for the entire cohort. The images are divided into two archive files due to uploading file size limitations - we apologize for the inconvenience. The files are organized by field of view (FOV), with each FOV subfolder containing TIF images for each channel that have undergone low-level processing as described...
- Subject
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ArteriesCell LineageImage Processing, Computer-AssistedMaternal-Fetal Exchange
- Access Rights
- Free to All