Description from BioProject: "The lifecycle of M. tuberculosis within the human host is marked by critical transition points between the major phases of infection: Initial infection, latent disease, active tuberculosis, and resolution with antibiotic therapy. Through observation of patients in each of these stages, we have some knowledge about host determinants that maintain each of these stages,...

Summary from GEO: "Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that recognize microbial vitamin B metabolites and have emerging roles in infectious disease, autoimmunity, and cancer. Although MAIT cells are identified by a semi-invariant T cell receptor, their phenotypic and functional heterogeneity is not well understood. Here we present an integrated single cell transcriptomic...

Summary from GEO: "We report the transcriptional changes of MAIT and Vd2 cells in the patients receiving allogeneic stem cell transplantation with good outcome compared to MAIT and Vdelta2 cells of healthy volunteers" Overall design from GEO: "Comparison of MAIT and Vd2 cells collected from 5 patients and 5 healthy control subjects"