Integrative analysis reveals unique structural and functional features of the Smc5/6 complex

Authors

Kentsis, Alex

Description

Cross-linking mass spectrometry data for integrative structural analyses of the Smc5/6 holo-complex from budding yeast. Electron microscopy, crosslinking mass spectrometry, and computational modeling reveal that while the complex shares an overall organization with other SMC complexes, it possesses several strikingly different features.

Subject

Computer Simulation

Mass spectrometry

Microscopy, Electron

Multiprotein Complexes

Access Rights

Free to All