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Replication-coupled nucleosome assembly and positioning by ATP-dependent chromatin remodeling enzymes
- Authors
- Yadav, TejasWhitehouse, Iestyn
- Description
Summary from GEO: "We have previously shown that Okazaki fragments in Saccharomyces cerevisiae are sized according to the chromatin repeat. Here we demonstrate that nucleosome positioning is rapidly established on newly synthesized DNA. Using deep sequencing, we demonstrate that ATP-dependent chromatin remodeling enzymes, Isw1 and Chd1, collaborate with histone chaperones, such as CAF-1 and Rtt106,...
- Subject
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ChromatinDNA Ligase ATPDNA ReplicationHigh-Throughput Nucleotide SequencingNucleosomes
- Access Rights
- Free to All
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Nucleosome Positioning Dynamics Through the Yeast Metabolic Cycle
- Authors
- Nocetti, NicolasWhitehouse, Iestyn
- Description
Summary from GEO: "We present Micrococcal Nuclease digestion maps of S. cerevisiae through the progression of the Yeast Metabolic Cycle. We demonstrate that nucleosome positions at many promoters are dynamic, and remodeling events at promoters have significant consequences with respect to gene expression." Overall design from GEO: "Examination of nucleosome positions and transcriptional output...
- Subject
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Gene ExpressionMicrococcal NucleaseNucleosomesTranscription, GeneticYeasts/metabolism
- Access Rights
- Free to All