Chromatin interaction of ERG and AR in established prostate cancer

Authors

Carver, Brett S.

Description

Summary from GEO: "The current study defines the how ERG, PTEN, and AR inteact to regulate the transciptome in established prostate cancers. Prostate cancer organoids were derived from established prostate cancer in GEM models harboring ERG over-expression and/or loss of PTEN and cultured in vitro using prostate epithelial organoid culture conditions. The established organoids were then isolated...

Subject

Chromatin Immunoprecipitation Sequencing

CRISPR-Cas Systems

Prostatic Neoplasms

PTEN Phosphohydrolase

Transcriptional Regulator ERG

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