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An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression
- Authors
- Albanese, Steven KyleParton, Daniel LawrenceIsik, MehtapRodriguez-Laureano, Lucelenie7 more author(s)...
- Description
Source code, assay data, full expression results for all ABL1 constructs, wild-type kinases, and ABL1 and SRC mutants, plasmid libraries, and other supporting material for the generation of a library of human kinase domain constructs for automated bacterial expression. From the publication abstract, "Kinases play a critical role in cellular signaling and are dysregulated in a number of diseases,...
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Bacteria/metabolismBinding sitesEscherichia coli/metabolismPhosphorylationProtein Structure, SecondaryProtein-Tyrosine KinasesProto-Oncogene Proteins c-ablsrc-Family Kinases
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- Free to AllFee Required
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Cryo-EM structure of the mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea
- Authors
- Long, Stephen BarstowBaradaran, RozbehWang, Chongyuan
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in the deposit, and version...
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AscomycotaCalcium ChannelsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
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- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
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- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
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- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with pppApApA
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...
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Cryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
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- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with pppApA
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...
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Cryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
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- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with AMPPNP
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes Crystal structure data of Csm1-Csm4 cassette in complex with AMPPNP. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history and funding identification. Data is provided for...
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Adenylyl ImidodiphosphateCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
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- Free to All
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Crystal structure of apo Csm1-Csm4 cassette
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Crystal structure of apo Csm1-Csm4 cassette. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history and funding identification....
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Cryoelectron MicroscopyNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
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- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with cA3
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA3. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...
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Carbonic AnhydrasesClustered Regularly Interspaced Short Palindromic RepeatsCryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
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- Free to All