Validation of itaconate modification on model proteins

Authors

Kentsis, Alex

Description

This dataset was generated to confirm that +130 and +146 Da adducts observed in LPS-stimulated macrophages were produced by the itaconate metabolite. To this end, model proteins (bovine serum albumin and human KEAP1) were reacted in vitro with itaconate, and the correspondent adducts were analyzed by LC-MSMS

Subject

Dicarboxylic Acids

Liquid Chromatography-Mass Spectrometry

Peptides

Recombinant Proteins

Access Rights

Free to All