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  • Rectal Cancer (MSK,Nature Medicine 2019): MSK-IMPACT targeted sequencing of matched rectal cancer tumor and tumoroid samples

    Authors
    Ganesh, Karuna
    Wu, Chao
    O'Rourke, Kevin Patrick
    Szeglin, Bryan Charles
    46 more author(s)...
    Description

    This dataset contains summary data visualizations and clinical data of rectal cancer tumoroids based on massively parallel sequencing using the custom, Food and Drug Administration (FDA)-cleared tumor-profiling panel MSK Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT). The clinical data includes mutation count, information about mutated genes, Gene Panel, Impact TMB Score,...

    Subject
    DNA Mutational Analysis
    Rectal Neoplasms
    Rectal Neoplasms/genetics
    Access Rights
    Free to All
  • Colorectal Adenocarcinoma (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 594 colorectal adenocarcinomas from 594 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    Adenocarcinoma, Mucinous
    Colonic Neoplasms
    Colorectal Neoplasms
    DNA Mutational Analysis
    Rectal Neoplasms
    Access Rights
    Free to All
  • MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay

    Description

    This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Adenocarcinoma, Mucinous
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Hepatocellular
    Carcinoma, Lobular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Carcinosarcoma
    Cholangiocarcinoma
    Colonic Neoplasms
    Colorectal Neoplasms
    Cystadenocarcinoma, Serous
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Glioblastoma
    Liposarcoma
    Lung Neoplasms
    Lymphoma, Follicular
    Melanoma
    Mesothelioma
    Neoplasms, Squamous Cell
    Neurofibroma
    Oligodendroglioma
    Osteosarcoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Prostatic Neoplasms
    Rectal Neoplasms
    Sarcoma
    Sarcoma, Synovial
    Squamous Cell Carcinoma of Head and Neck
    Stomach Neoplasms
    Thyroid Cancer, Papillary
    Urinary Bladder Neoplasms
    Uterine Neoplasms
    Uveal Neoplasms
    Access Rights
    Free to All
  • The Angiosarcoma Project - Count Me In (Nature Medicine, 2020)

    Description

    Dataset Summary Description: "The Angiosarcoma Project is an ongoing patient-driven initiative. This archived Angiosarcoma Project dataset was analyzed in the linked Nature Medicine 2020 manuscript, and is derived from 48 samples from 36 angiosarcoma patients. Angiosarcoma tumor specimens (FFPE) were subjected to whole-exome sequencing (along with matched germline whole-exome sequencing). In addition...

    Subject
    Adenocarcinoma
    Basal Cell Carcinoma
    Breast Neoplasms
    Hemangiosarcoma
    Hodgkin Disease
    Leukemia, Lymphocytic, Chronic, B-Cell
    Rectal Neoplasms
    Skin Neoplasms
    Thyroid Neoplasms
    Uterine Neoplasms
    Vulvar Neoplasms
    Access Rights
    Free to All
  • The Angiosarcoma Project (Provisional): an ongoing patient-driven initiative.

    Description

    Dataset Summary Description: "This provisional dataset is currently derived from 83 samples, including tumor specimens (FFPE and cfDNA) from 62 angiosarcoma patients subjected to WES (along with matched germline WES). This study includes genomic data, patient-reported data (pre-pended as PRD), medical record data (MedR), and pathology report data (PATH). As these data were generated in a research...

    Subject
    Basal Cell Carcinoma
    Breast Neoplasms
    Colorectal Neoplasms
    Hemangiosarcoma
    Hodgkin Disease
    Leukemia, Lymphocytic, Chronic, B-Cell
    Prostatic Neoplasms
    Rectal Neoplasms
    Skin Neoplasms
    Thyroid Neoplasms
    Uterine Neoplasms
    Vulvar Neoplasms
    Access Rights
    Free to All